BDBM50652650 CHEMBL5646860

SMILES Nc1nonc1-c1nc2cccc(F)c2n1Cc1cccnn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50652650   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Cerevance Limited

Curated by ChEMBL
LigandPNGBDBM50652650(CHEMBL5646860)
Affinity DataIC50: 24nMAssay Description:Inhibition of NLRP3 inflammasome-mediated IL-1beta release in LPS-primed neonatal C57BL/6 P1-4 mouse microglia pretreated for 30 mins followed by med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPotassium channel subfamily K member 13(Mus musculus)
Cerevance Limited

Curated by ChEMBL
LigandPNGBDBM50652650(CHEMBL5646860)
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse KCNK13 transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPotassium channel subfamily K member 13(Mus musculus)
Cerevance Limited

Curated by ChEMBL
LigandPNGBDBM50652650(CHEMBL5646860)
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse KCNK13 transfected in HEK293 cells assessed as reduction in thallium influx incubated for 15 mins in dark by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPotassium channel subfamily K member 13(Homo sapiens)
Cerevance Limited

Curated by ChEMBL
LigandPNGBDBM50652650(CHEMBL5646860)
Affinity DataIC50: 41nMAssay Description:Inhibition of human KCNK13 transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPotassium channel subfamily K member 13(Homo sapiens)
Cerevance Limited

Curated by ChEMBL
LigandPNGBDBM50652650(CHEMBL5646860)
Affinity DataIC50: 41nMAssay Description:Inhibition of human KCNK13 transfected in HEK293 cells assessed as reduction in thallium influx incubated for 15 mins in dark by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed