BDBM50652667 CHEMBL5639421

SMILES FC1(F)CNCC(CNc2nc(-c3ccc(N4CCOCC4)cc3)cc3nccnc23)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50652667   

TargetTyrosine-protein kinase SYK(Human)
HUTCHMED Limited

Curated by ChEMBL
LigandPNGBDBM50652667(CHEMBL5639421)
Affinity DataIC50: 50nMAssay Description:Inhibition of Syk (unknown origin) incubated for 1 hr in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
HUTCHMED Limited

Curated by ChEMBL
LigandPNGBDBM50652667(CHEMBL5639421)
Affinity DataIC50: 216nMAssay Description:Inhibition of Syk (unknown origin) at 3 uM incubated for 1 hr in presence of ATP by FRET assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed