BDBM50652682 CHEMBL5647595

SMILES CC(=O)N1CCC(c2ccc(-c3cc4nccnc4c(NC[C@@H]4CNCCO4)n3)cc2F)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50652682   

TargetTyrosine-protein kinase SYK(Human)
HUTCHMED Limited

Curated by ChEMBL
LigandPNGBDBM50652682(CHEMBL5647595)
Affinity DataIC50: 53nMAssay Description:Inhibition of Syk (unknown origin) at 3 uM incubated for 1 hr in presence of ATP by FRET assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
HUTCHMED Limited

Curated by ChEMBL
LigandPNGBDBM50652682(CHEMBL5647595)
Affinity DataIC50: 75nMAssay Description:Inhibition of Syk (unknown origin) incubated for 1 hr in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
HUTCHMED Limited

Curated by ChEMBL
LigandPNGBDBM50652682(CHEMBL5647595)
Affinity DataIC50: 263nMAssay Description:Inhibition of his-tagged human recombinant KDR incubated for 60 mins by Z'lyte assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed