BDBM506527 US11045457, Example 127

SMILES CC[C@H]1CN(C)CC[C@@H]1NC(=O)C(C)(C)COc1ncccc1C

InChI Key InChIKey=BWYRNJOJEXHYRA-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 506527   

TargetSomatostatin receptor type 4(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 506527BDBM506527(US11045457, Example 127)
Affinity DataIC50: 79.4nMAssay Description:This membrane-based assay measures the ability of compounds to competitively inhibit binding of I-125 labeled somatostatin to SSTR4 in membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetSomatostatin receptor type 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 506527BDBM506527(US11045457, Example 127)
Affinity DataIC50: 7.94E+3nMAssay Description:This membrane-based assay measures the ability of compounds to competitively inhibit binding of I-125 labeled somatostatin to SSTR1 in membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent