BDBM50652794 CHEMBL5661872
SMILES Cc1[nH]c(/C=C2/C(=O)Nc3ccc(S(=O)(=O)N(C)c4cccc(Cl)c4)cc32)c(C)c1C(=O)N1CCN(C)CC1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50652794
Affinity DataIC50: 20nMAssay Description:Inhibition of glutathione S-transferase fused Met (unknown origin) catalytic activity infected in Sf9 cells using poly-Glu-Tyr (4:1) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HGF-dependent Met (unknown origin) phosphorylationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of glutathione S-transferase fused Flk1 (unknown origin) catalytic activity infected in Sf9 cells using poly-Glu-Tyr (4:1) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of c-Met in human bortezomib-resistant ANBL6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one s...More data for this Ligand-Target Pair
Affinity DataIC50: 5.92E+3nMAssay Description:Inhibition of c-MET in human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prol...More data for this Ligand-Target Pair
Affinity DataIC50: 8.91E+3nMAssay Description:Inhibition of c-Met in Melphalan Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous on...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of glutathione S-transferase fused FGFR1 (unknown origin) catalytic activity infected in Sf9 cells using poly-Glu-Tyr (4:1) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Met in human U-266 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolifer...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Met in human ANBL-6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolife...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glutathione S-transferase fused CDK2 (unknown origin) catalytic activity infected in Sf9 cells using poly-Glu-Tyr (4:1) as substrateMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glutathione S-transferase fused c-Src (unknown origin) catalytic activity infected in Sf9 cells using poly-Glu-Tyr (4:1) as substrateMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of glutathione S-transferase fused PDGFbetaR (unknown origin) catalytic activity infected in Sf9 cells using poly-Glu-Tyr (4:1) as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of glutathione S-transferase fused Tie2 (unknown origin) catalytic activity infected in Sf9 cells using poly-Glu-Tyr (4:1) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of glutathione S-transferase fused EGFR (unknown origin) catalytic activity infected in Sf9 cells using poly-Glu-Tyr (4:1) as substrateMore data for this Ligand-Target Pair