BDBM50652844 CHEMBL5661849

SMILES Cc1c(NC(=O)c2cc(C(N)=O)nc3ccc(F)cc23)c(C(F)(F)F)nn1Cc1ccc(C#N)cc1

InChI Key InChIKey=HBXKXXRRQJIJRG-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50652844   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Bayer AG

Curated by ChEMBL

LigandBDBM50652844(CHEMBL5661849)Copy SMILESCopy InChI

Affinity DataIC50: 5nMAssay Description:Inhibition of human GLUT1 expressed in human DLD-1 cells assessed as reduction in glucose uptake by measuring decrease in ATP production incubated fo...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG

Curated by ChEMBL

LigandBDBM50652844(CHEMBL5661849)Copy SMILESCopy InChI

Affinity DataIC50: 44nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 3(Human)
Bayer AG

Curated by ChEMBL

LigandBDBM50652844(CHEMBL5661849)Copy SMILESCopy InChI

Affinity DataIC50: 290nMAssay Description:Inhibition of human GLUT3 expressed in human GLUT1-/- DLD-1 cells assessed as reduction in glucose uptake by measuring decrease in ATP production inc...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL