BDBM50652928 CHEMBL5687007

SMILES CCCCN(CCCC)C(=O)CN1[C@H](c2cc(OC)c3c(c2)OCO3)C[C@@H](C(=O)O)[C@@H]1CC(C)(C)CCC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50652928   

TargetEndothelin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50652928(CHEMBL5687007)
Affinity DataKi:  0.460nMAssay Description:Displacement of [125I]endhothelin-1 from human ETA receptor stably expressed in CHO cells Membrane assessed as inhibition constant at 25 degC incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndothelin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50652928(CHEMBL5687007)
Affinity DataIC50: 0.490nMAssay Description:Displacement of [125I]endhothelin-1 from human ETA receptor stably expressed in CHO cells Membrane at 25 degC incubated for 3 hrs by radioligand comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50652928(CHEMBL5687007)
Affinity DataIC50: 0.560nMAssay Description:Displacement of [125I]endhothelin-1 from ETA receptor in rat MMQ cells Membrane at 25 degC incubated for 3 hrs by radioligand competition binding ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndothelin receptor type B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50652928(CHEMBL5687007)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of [125I]endhothelin-3 from human ETB receptor stably expressed in CHO cells Membrane assessed as inhibition constant at 25 degC incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndothelin receptor type B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50652928(CHEMBL5687007)
Affinity DataIC50: 1.54E+4nMAssay Description:Displacement of [125I]endhothelin-3 from human ETB receptor stably expressed in CHO cells Membrane at 25 degC incubated for 3 hrs by radioligand comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50652928(CHEMBL5687007)
Affinity DataIC50: 1.67E+4nMAssay Description:Displacement of [125I]endhothelin-3 from ETB receptor in porcine Cerebellum Membrane at 25 degC incubated for 3 hrs by radioligand competition bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed