BDBM50652937 CHEMBL5687044

SMILES CC(=O)Nc1nc(C)c(-c2cnc(Cl)c(NS(C)(=O)=O)c2)s1

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50652937   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
AstraZeneca

Curated by ChEMBL

LigandBDBM50652937(CHEMBL5687044)Copy SMILES

Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate preincubated for 20 mins followed by substrate and ATP addition and measured after ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
AstraZeneca

Curated by ChEMBL

LigandBDBM50652937(CHEMBL5687044)Copy SMILES

Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PI3Kbeta using PIP2 as substrate preincubated for 20 mins followed by substrate and ATP addition and measured after 2...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL