BDBM50652978 CHEMBL5705846

SMILES CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5cc(OC)c(OC)cc45)c3)cc2C(F)(F)F)CC1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50652978   

TargetMitogen-activated protein kinase kinase kinase kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50652978(CHEMBL5705846)
Affinity DataIC50: 31nMAssay Description:Inhibition of MAP4K2 (unknown origin) Lys1 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Fer(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50652978(CHEMBL5705846)
Affinity DataIC50: 36nMAssay Description:Inhibition of FER (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50652978(CHEMBL5705846)
Affinity DataIC50: 51nMAssay Description:Inhibition of FES (unknown origin) by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50652978(CHEMBL5705846)
Affinity DataIC50: 129nMAssay Description:Inhibition of TAK1 (unknown origin) Lys2 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed