BDBM50652983 CHEMBL5705835

SMILES CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(OCc4cnc5[nH]ccc5c4OC)c3)cc2C(F)(F)F)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50652983   

TargetMitogen-activated protein kinase kinase kinase kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50652983(CHEMBL5705835)
Affinity DataIC50: 49nMAssay Description:Inhibition of MAP4K2 (unknown origin) Lys1 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase CSK(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50652983(CHEMBL5705835)
Affinity DataIC50: 59nMAssay Description:Inhibition of CSK (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50652983(CHEMBL5705835)
Affinity DataIC50: 150nMAssay Description:Inhibition of TAK1 (unknown origin) Lys2 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50652983(CHEMBL5705835)
Affinity DataIC50: 659nMAssay Description:Inhibition of p38 alpha (unknown origin) by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed