BDBM50653001 CHEMBL5712056

SMILES O=S(=O)(NCCNC/C=C/c1ccc(Br)cc1)Nc1cccc2cnccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50653001   

TargetRho-associated protein kinase 2(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50653001(CHEMBL5712056)
Affinity DataIC50: 290nMAssay Description:Inhibition of His6-tagged ROCK2 (2 to 543 residues) (unknown origin) using peptide as substrate incubated for 15 mins in presence of ATP by immunoblo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50653001(CHEMBL5712056)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged LRRK2 (1326 to 2527 residues) (unknown origin) using peptide as substrate incubated for 15 mins in presence of ATP by immuno...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50653001(CHEMBL5712056)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged LRRK2 G2019S mutant (1326 to 2527 residues) (unknown origin) using peptide as substrate incubated for 15 mins in presence of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed