BDBM50653056 CHEMBL5722954

SMILES COc1ccccc1-c1cc(Nc2cccc(NS(C)(=O)=O)c2)ncn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50653056   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataKd:  33nMAssay Description:Displacement of kinase tracer 236 from CDK9/Cyclin T1 (unknown origin) assessed as dissociation constant incubated for 1 hr by LanthScreen Eu kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataIC50: 44nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) using ULight MBP peptide as substrate in presence of ATP incubated for 1 hr by FRET based LANCE Ultra K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataIC50: 820nMAssay Description:Inhibition of MAP4K4 (unknown origin) incubated for 120 mins in presence of 33P-ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of GSK3A (unknown origin) incubated for 120 mins in presence of 33P-ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL2(Human)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataIC50: 3.64E+3nMAssay Description:Inhibition of ABL2 (unknown origin) incubated for 120 mins in presence of 33P-ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 (unknown origin) using ULight MBP peptide as substrate in presence of ATP incubated for 1 hr by FRET based LANCE Ultra K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataIC50: 9.24E+3nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) using ULight MBP peptide as substrate in presence of ATP incubated for 1 hr by FRET based LANCE Ultra K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK6/Cyclin D3 (unknown origin) using ULight MBP peptide as substrate in presence of ATP incubated for 1 hr by FRET based LANCE Ultra K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 (unknown origin) using ULight MBP peptide as substrate in presence of ATP incubated for 1 hr by FRET based LANCE Ult...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataKd:  1.60E+4nMAssay Description:Displacement of kinase tracer 236 from CDK7/Cyclin H/MAT1 (unknown origin) assessed as dissociation constant incubated for 1 hr by LanthScreen Eu kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Human)
Westfalian Wilhelms University Muenster (WWU)

Curated by ChEMBL
LigandPNGBDBM50653056(CHEMBL5722954)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CAMK4 (unknown origin) incubated for 120 mins in presence of 33P-ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed