BDBM50653061 CHEMBL5723005

SMILES CCC(=O)N1CCN(c2ccc(N3C(=O)CCc4cnc5ccc(-c6cnc7ccccc7c6)cc5c43)cc2C(F)(F)F)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50653061   

LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50:  171nMAssay Description:Inhibition of PI3K gamma (unknown origin) by drug competition for substrate binding based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50:  176nMAssay Description:Inhibition of PIK3C2A (unknown origin) by drug competition for substrate binding based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50:  200nMAssay Description:Inhibition of human PI3Kbeta assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50:  200nMAssay Description:Inhibition of PI3K beta (unknown origin) by drug competition for substrate binding based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50:  250nMAssay Description:Inhibition of PI3K alpha (unknown origin) by drug competition for substrate binding based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50:  533nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50:  549nMAssay Description:Inhibition of PIK3C2B (unknown origin) by drug competition for substrate binding based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50:  784nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50:  6.68E+3nMAssay Description:Inhibition of PI4KB (unknown origin) by drug competition for substrate binding based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50653061(CHEMBL5723005)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human PI3Kbeta assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed