BDBM50653108 CHEMBL5722981

SMILES CN(c1ncccc1CNc1nc(Nc2ccc3c(c2)CCC(=O)N3)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50653108   

TargetFocal adhesion kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50653108(CHEMBL5722981)
Affinity DataKi:  3.20nMAssay Description:Inhibition of full-length FAK (unknown origin) with N-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein-tyrosine kinase 2-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50653108(CHEMBL5722981)
Affinity DataKi:  8.40nMAssay Description:Inhibition of full-length PYK2 (unknown origin) with C-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed