BDBM50653340 CHEMBL6133757
SMILES COc1cc(Nc2ccc3c(n2)CN(C)C32CCN(C3COC3)CC2)c(C(N)=O)nc1-c1cccc2c1ncn2C
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 32 hits for monomerid = 50653340
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:Agonist activity at human PPARalpha receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataEC50: 43nMAssay Description:Agonist activity at human PPARgamma receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 116nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 185nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 317nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 325nMAssay Description:Agonist activity at human PPARgamma receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 325nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 377nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 500nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 521nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 2(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 1.74E+3nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.89E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 2.11E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 2.99E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
TargetInterleukin-1 receptor-associated kinase 4(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.14E+3nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Insilico Medicine Shanghai Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Ligand Info
