BDBM50653554 CHEMBL6142905

SMILES COC1CCN(c2nccc(Nc3cc4n([C@@H]5CC[C@H](C)C5)c(C)cn4n3)n2)CC1

InChI Key InChIKey=YANSEIYMYYCSEL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50653554   

TargetEpidermal growth factor receptor(Human)
Schrodinger Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653554BDBM50653554(CHEMBL6142905)
Affinity DataKi:  32nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Schrodinger Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653554BDBM50653554(CHEMBL6142905)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of GCS by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed