BDBM50653919 CHEMBL6150030

SMILES CS(=O)(=O)Nc1ccc(-c2ccnc(Nc3ccc(N4CCN(CC(=O)Nc5ccc(C(=O)NO)cc5)CC4)cc3)n2)cc1

InChI Key InChIKey=DBOSQKGNJZTGTC-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50653919   

TargetTyrosine-protein kinase JAK2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 0.490nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 8.30nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 38nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 89nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 105nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 989nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed