BDBM50653993 CHEMBL6142721

SMILES Cc1cc(-c2ccc(C#N)cc2)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(F)cc3)CC2)ncc1CO

InChI Key InChIKey=DEUUOXROGWZPFN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50653993   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653993BDBM50653993(CHEMBL6142721)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human ERbeta LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653993BDBM50653993(CHEMBL6142721)
Affinity DataIC50: 2.95E+5nMAssay Description:Inhibition of PI3Kalpha-mediated AKT phosphorylation at S473 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed