BDBM50654151 CHEMBL6120377

SMILES N#Cc1ccc(Cn2c3ccc(Cl)cc3c3cc(C(=O)NCc4ccccn4)ncc32)cc1

InChI Key InChIKey=BDHRUEDKFUTDIH-UHFFFAOYSA-N

Data  8 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50654151   

TargetNAD-dependent protein deacylase sirtuin-6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654151BDBM50654151(CHEMBL6120377)
Affinity DataIC50: 5.68E+3nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654151BDBM50654151(CHEMBL6120377)
Affinity DataIC50: 5.81E+3nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654151BDBM50654151(CHEMBL6120377)
Affinity DataKd:  1.65E+4nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654151BDBM50654151(CHEMBL6120377)
Affinity DataIC50: 1.57E+5nMAssay Description:Positive allosteric modulation of calcium sensing receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654151BDBM50654151(CHEMBL6120377)
Affinity DataIC50: 1.57E+5nMAssay Description:Positive allosteric modulation of calcium sensing receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNAD-dependent protein lipoamidase sirtuin-4, mitochondrial(Homo sapiens)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654151BDBM50654151(CHEMBL6120377)
Affinity DataIC50: 2.74E+5nMAssay Description:Positive allosteric modulation of calcium sensing receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654151BDBM50654151(CHEMBL6120377)
Affinity DataIC50: 3.12E+5nMAssay Description:Positive allosteric modulation of calcium sensing receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654151BDBM50654151(CHEMBL6120377)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human ERG by cell based by patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654151BDBM50654151(CHEMBL6120377)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed