BDBM50654305 CHEMBL6102777

SMILES [2H]C([2H])([2H])C([2H])([2H])[S+]([O-])c1cc(Cl)ccc1Nc1nc(Nc2cc(NC(=O)C=C)c(N(C)CCN(C)C)cc2OC)ncc1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50654305   

TargetEpidermal growth factor receptor(Human)
Binzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654305BDBM50654305(CHEMBL6102777)
Affinity DataIC50: 3.60nMAssay Description:Negative allosteric modulation of mGlu5 receptor (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50654305BDBM50654305(CHEMBL6102777)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction of EPO-induced STAT5 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed