BDBM50654307 CHEMBL6143027

SMILES [2H]C([2H])([2H])C([2H])([2H])[S+]([O-])c1c(F)cccc1Nc1nc(Nc2cc(NC(=O)C=C)c(N(C)CCN(C)C)cc2OC)ncc1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50654307   

TargetEpidermal growth factor receptor(Human)
Binzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654307BDBM50654307(CHEMBL6143027)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at CGRP receptor (unknown origin) by cell based cAMP assay in presence of human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50654307BDBM50654307(CHEMBL6143027)
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity at human alpha4beta2 nAChR assessed as inhibition of nicotine-induced [86Rb+] efflux preincubated for 10 mins before nicotine exp...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed