BDBM50654312 CHEMBL6144949

SMILES C=CC(=O)Nc1cc(Nc2ncc(Cl)c(Nc3cccc(Cl)c3[S+]([O-])C(C)C)n2)c(OC)cc1N(C)CCN(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50654312   

TargetEpidermal growth factor receptor(Human)
Binzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654312BDBM50654312(CHEMBL6144949)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of JAK1 (unknown origin) assessed as reduction of IL6-induced STAT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50654312BDBM50654312(CHEMBL6144949)
Affinity DataIC50: 7.40nMAssay Description:Agonist activity at human alpha4beta2 nAChR assessed as stimulation of [86Rb+] efflux after 2 mins by cell-based liquid scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed