BDBM50654488 CHEMBL6146573

SMILES C=CC(=O)N1CCC[C@@H](n2nc(-c3ccc(OCc4cccc(C)n4)cc3)c3c(N)ncnc32)C1

InChI Key InChIKey=NPZRSECAABLJCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50654488   

TargetEpidermal growth factor receptor(Human)
Affiliated Cancer Hospital of University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654488BDBM50654488(CHEMBL6146573)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of 1,10-phenanthrolin-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by cell-based luciferase reporter...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Affiliated Cancer Hospital of University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654488BDBM50654488(CHEMBL6146573)
Affinity DataIC50: 16nMAssay Description:Inhibition of gamma-secretase mediated amyloid beta-40 production in HEK293 cells by whole cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed