BDBM50654491 CHEMBL6133515

SMILES C=CC(=O)N1CCN(c2ncc3ncnc(Nc4ccc(Oc5ccn6ncnc6c5)c(C)c4)c3n2)CC1

InChI Key InChIKey=KXUBSQUYDKKQTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50654491   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Affiliated Cancer Hospital of University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654491BDBM50654491(CHEMBL6133515)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of 1,10-phenanthrolin-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by cell-based luciferase reporter...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Affiliated Cancer Hospital of University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654491BDBM50654491(CHEMBL6133515)
Affinity DataIC50: 2.20E+3nMAssay Description:Agonist activity at Homo sapiens (human) 5-HT2C receptor assessed as calcium mobilization by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed