BDBM50654786 CHEMBL6162898

SMILES Cn1cc(-c2ccc3c(c2)ncn3-c2ccc(CC(=O)Nc3cc(C(C)(C)C)no3)cc2)cn1

InChI Key InChIKey=VIQAAPJVSOWKQK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50654786   

TargetPlatelet-derived growth factor receptor alpha(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654786BDBM50654786(CHEMBL6162898)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654786BDBM50654786(CHEMBL6162898)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of IDO1 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654786BDBM50654786(CHEMBL6162898)
Affinity DataIC50: 1.20nMAssay Description:Agonist activity at FXR (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654786BDBM50654786(CHEMBL6162898)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as reduction in amyloidbeta 40 level after 24 hrs by cell-based sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654786BDBM50654786(CHEMBL6162898)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654786BDBM50654786(CHEMBL6162898)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human Nav1.5 at -50 mV holding potential by cell-based IonWorks barracuda automated electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed