BDBM50654787 CHEMBL6148321

SMILES Cn1cc(-c2ccc3c(c2)ncn3-c2ccc(CC(=O)Nc3cc(-c4ccccc4)no3)cc2)cn1

InChI Key InChIKey=SAVMVMNHDOGGHR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50654787   

TargetVascular endothelial growth factor receptor 2(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654787BDBM50654787(CHEMBL6148321)
Affinity DataIC50: 14nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as reduction in amyloidbeta 40 level after 24 hrs by cell-based sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654787BDBM50654787(CHEMBL6148321)
Affinity DataIC50: 18nMAssay Description:Agonist activity at FXR (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654787BDBM50654787(CHEMBL6148321)
Affinity DataIC50: 42nMAssay Description:Inhibition of human Nav1.5 at -50 mV holding potential by cell-based IonWorks barracuda automated electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed