BDBM50654788 CHEMBL6150730

SMILES CC(C)(C)c1cc(NC(=O)Cc2ccc(-n3cnc4cc(-c5cn[nH]c5)ccc43)cc2)on1

InChI Key InChIKey=KLCBEXKZLLKSAW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50654788   

TargetPlatelet-derived growth factor receptor alpha(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654788BDBM50654788(CHEMBL6150730)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654788BDBM50654788(CHEMBL6150730)
Affinity DataIC50: 0.330nMAssay Description:Agonist activity at human A2B adenosine receptor by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654788BDBM50654788(CHEMBL6150730)
Affinity DataIC50: 0.890nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654788BDBM50654788(CHEMBL6150730)
Affinity DataIC50: 1nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as reduction in amyloidbeta 40 level after 24 hrs by cell-based sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654788BDBM50654788(CHEMBL6150730)
Affinity DataIC50: 1.40nMAssay Description:Agonist activity at FXR (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654788BDBM50654788(CHEMBL6150730)
Affinity DataIC50: 2nMAssay Description:Inhibition of human Nav1.7 at -60 mV holding potential by cell-based IonWorks barracuda automated electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed