BDBM50655040 CHEMBL6171065

SMILES CC(C)CNC1c2ccccc2C=Cc2ccccc21

InChI Key InChIKey=QJKWIVAIHIGFRX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50655040   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655040BDBM50655040(CHEMBL6171065)
Affinity DataIC50: 160nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655040BDBM50655040(CHEMBL6171065)
Affinity DataIC50: 360nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655040BDBM50655040(CHEMBL6171065)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655040BDBM50655040(CHEMBL6171065)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed