BDBM50655201 CHEMBL6162994

SMILES N#Cc1c(-c2ccc(Cl)s2)nc(SCc2cccc(Cl)c2)[nH]c1=O

InChI Key InChIKey=GWZODROUQYVGIM-UHFFFAOYSA-N

Data  10 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50655201   

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 32nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 71nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 390nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 715nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 1.28E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 1.43E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 1.43E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 2.88E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655201(CHEMBL6162994)Copy SMILESCopy InChI

Affinity DataIC50: 2.92E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL