BDBM50655213 CHEMBL6167402

SMILES CC(Sc1nc(-c2ccc(Cl)s2)c(C#N)c(=O)[nH]1)c1cccc(Cl)c1

InChI Key InChIKey=NCSNPJMAUHDDIM-UHFFFAOYSA-N

Data  10 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50655213   

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 11nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 263nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
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TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 357nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 681nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
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TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 1.82E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
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TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 2.09E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
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TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 2.39E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
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TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 3.01E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
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TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 4.62E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
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TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50655213(CHEMBL6167402)Copy SMILESCopy InChI

Affinity DataIC50: 5.16E+3nMAssay Description:Modulation of mouse Utrophin in mouse myoblast expressing LUmdx assessed as upregulation of utrophin mRNA expression incubated for 24 hrs by cell-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
6/4/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL