BDBM50655334 CHEMBL6103492

SMILES Nc1nc(N)c(NC(=O)Nc2ccc(C(=O)N[C@@H](CCc3nnn[nH]3)C(=O)O)cc2Cl)c(=O)[nH]1

InChI Key

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50655334   

TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655334BDBM50655334(CHEMBL6103492)
Affinity DataIC50: 40nMAssay Description:Inhibition of NKG2D (unknown origin)/ULBP6 (unknown origin) protein-protein interaction by cell-based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655334BDBM50655334(CHEMBL6103492)
Affinity DataIC50: 230nMAssay Description:Inhibition of NKG2D (unknown origin)/ULBP6 (unknown origin) protein-protein interaction by cell-based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)