BDBM50655509 CHEMBL6133134

SMILES c1ccc2c(c1)cc(cn2)C#Cc3cn(c4c3c(ncn4)N)[C@H]5[C@@H]([C@@H]([C@H](O5)CSCC[C@@H](C(=O)O)N)O)O

InChI Key InChIKey=SPMFBZXXQBXKFX-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50655509   

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655509BDBM50655509(CHEMBL6133134)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV nsp14 extracted from Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655509BDBM50655509(CHEMBL6133134)
Affinity DataKd:  25nMAssay Description:Binding affinity to SARS-CoV-2 nsp14 assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed