BDBM50655577 CHEMBL6159898

SMILES Nc1ccc2ccc(CC[C@H]3C[C@@H](n4ccc5c(N6CCNCC6)ncnc54)[C@H](O)[C@@H]3O)cc2n1

InChI Key InChIKey=QFYQTAXQJULRHY-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50655577   

TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 3nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 3nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of PRMT4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GLP (unknown origin) preincubated with compound for 10 mins followed by peptide substrate/SAM addition and measured after 4 hrs by HTRF...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NSD3 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PRMT8 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of G9a (unknown origin) preincubated with compound for 10 mins followed by peptide substrate/SAM addition and measured after 4 hrs by HTRF...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of DNMT1 (unknown origin) preincubated with compound for 10 mins followed by peptide substrate/SAM addition and measured after 4 hrs by HT...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EZH2 (unknown origin) preincubated with compound for 10 mins followed by peptide substrate/SAM addition and measured after 4 hrs by HTR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NSD2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed