BDBM50655610 CHEMBL6162323

SMILES Cc1ccc(N/N=C(C(=O)O)C(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

InChI Key InChIKey=BPOKMWDYEYURFB-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50655610   

TargetLiver carboxylesterase(Pig)
Postovsky Institute of Organic Synthesis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655610BDBM50655610(CHEMBL6162323)
Affinity DataKi:  18nMAssay Description:Reversible mixed type inhibition of porcine liver carboxylesterase using 4-nitrophenylacetate as substrate assessed as inhibition constant of competi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLiver carboxylesterase(Pig)
Postovsky Institute of Organic Synthesis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655610BDBM50655610(CHEMBL6162323)
Affinity DataKi:  27nMAssay Description:Reversible mixed type inhibition of porcine liver carboxylesterase using 4-nitrophenylacetate as substrate assessed as inhibition constant of non-com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLiver carboxylesterase(Pig)
Postovsky Institute of Organic Synthesis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655610BDBM50655610(CHEMBL6162323)
Affinity DataIC50: 42nMAssay Description:Inhibition of porcine liver carboxylesterase using 4-nitrophenylacetate as substrate assessed as release of 4-nitrophenol by spectrophotometric analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLiver carboxylesterase 1(Human)
Postovsky Institute of Organic Synthesis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655610BDBM50655610(CHEMBL6162323)
Affinity DataIC50: 102nMAssay Description:Inhibition of human CES1 using 4-nitrophenylacetate as substrate assessed as release of 4-nitrophenol by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCocaine esterase(Human)
Postovsky Institute of Organic Synthesis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655610BDBM50655610(CHEMBL6162323)
Affinity DataIC50: 109nMAssay Description:Inhibition of human CES2 using 4-nitrophenylacetate as substrate assessed as release of 4-nitrophenol by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed