BDBM50655816 CHEMBL6151671

SMILES C[C@@H]1[C@@H](C(=O)O)N(C(=O)c2cc(C3CC3)c(OCC34CC5CC(CC(C5)C3)C4)cc2F)C[C@@H]1F

InChI Key InChIKey=FOTAYVDKAXQYQD-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50655816   

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655816BDBM50655816(CHEMBL6151671)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]GX-545 from Nav1.7 VSD4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655816BDBM50655816(CHEMBL6151671)
Affinity DataIC50: 10nMAssay Description:Inhibition of human Nav1.7 by patch clamp electrophysiologyMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655816BDBM50655816(CHEMBL6151671)
Affinity DataIC50: 260nMAssay Description:Inhibition of human Nav1.7 by sodium flux assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655816BDBM50655816(CHEMBL6151671)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human Nav1.5 by patch clamp electrophysiologyMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed