BDBM50655826 CHEMBL6134275

SMILES O=C(c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F)C1CCC[C@H]1C(=O)O

InChI Key InChIKey=LJSRWUOUMKHPKL-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50655826   

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655826BDBM50655826(CHEMBL6134275)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]GX-545 from Nav1.7 VSD4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655826BDBM50655826(CHEMBL6134275)
Affinity DataIC50: 12nMAssay Description:Inhibition of human Nav1.7 by patch clamp electrophysiologyMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655826BDBM50655826(CHEMBL6134275)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Nav1.7 by sodium flux assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655826BDBM50655826(CHEMBL6134275)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human Nav1.5 by patch clamp electrophysiologyMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed