BDBM50655995 CHEMBL6144423

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CN2CCC(CCCOc3cnc4c(C5CCN(C(=O)c6ccc(OC(F)(F)F)cc6)CC5)ncnc4c3)CC2)C(C)(C)C)cc1

InChI Key InChIKey=OPTMQCZERNVQNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50655995   

TargetElongin-C(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655995BDBM50655995(CHEMBL6144423)
Affinity DataIC50: 610nMAssay Description:Binding affinity to VHL/Elongin C/Elogin B (unknown origin) incubated for 90 mins by FRET assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655995BDBM50655995(CHEMBL6144423)
Affinity DataIC50: 3.53E+4nMAssay Description:Binding affinity to VHL in human THP-1 cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed