BDBM50656362 CHEMBL6162011

SMILES CN(C)C1CN(c2nc3c(F)c(-c4cc(O)cc5ccccc45)c(Cl)cc3c3c2ncn3[C@H]2[C@H]3CN[C@@H]2C3)C1

InChI Key InChIKey=OAOCNUDAFDIMDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50656362   

TargetGTPase KRas(Human)
Incyte

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656362BDBM50656362(CHEMBL6162011)
Affinity DataIC50: 671nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed