BDBM50656743 CHEMBL6134398

SMILES Cn1cc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)/C=C/c4ccccc4)c3)n2)cn1

InChI Key InChIKey=VGQUMZFLTMXSON-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50656743   

TargetTyrosine-protein kinase JAK3(Human)
King Mongkut's Institute of Technology Ladkrabang

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656743BDBM50656743(CHEMBL6134398)
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK3 (unknown origin) using poly (Glu:Tyr) as substrate incubated for 1 hr in presence of ATP by ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
King Mongkut's Institute of Technology Ladkrabang

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656743BDBM50656743(CHEMBL6134398)
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFR DM T790M/L858R mutant (unknown origin) using poly (Glu:Tyr) as substrate incubated for 1 hr in presence of ATP by ADP-glo kinase a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
King Mongkut's Institute of Technology Ladkrabang

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656743BDBM50656743(CHEMBL6134398)
Affinity DataIC50: 45nMAssay Description:Inhibition of wild type EGFR (unknown origin) using poly (Glu:Tyr) as substrate incubated for 1 hr in presence of ATP by ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed