BDBM50656962 CHEMBL6144196
SMILES O=C(NCc1cc(F)ccc1F)c1c[nH]c(-c2ccc(OC(F)F)c(OCC3CC3)c2)n1
InChI Key InChIKey=MHIGZOWKEYONSA-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50656962
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE2A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE11A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE10A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE9A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE3A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE1A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE8A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE6C (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info