BDBM50657460 CHEMBL6167388

SMILES CCc1cc(S(C)(=O)=O)cc(F)c1N(C)c1cc2c(ncn2C)c(Nc2cnn(CC#N)c2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50657460   

TargetTyrosine-protein kinase JAK1(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657460BDBM50657460(CHEMBL6167388)
Affinity DataIC50: 0.420nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657460BDBM50657460(CHEMBL6167388)
Affinity DataIC50: 0.530nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657460BDBM50657460(CHEMBL6167388)
Affinity DataIC50: 0.590nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK3(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657460BDBM50657460(CHEMBL6167388)
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed