BDBM50657468 CHEMBL6151179

SMILES CCc1cc(C(N)=O)ccc1N(C)c1cc2c(ncn2C)c(NC(=O)[C@H]2C[C@H]2F)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50657468   

TargetTyrosine-protein kinase JAK1(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657468BDBM50657468(CHEMBL6151179)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657468BDBM50657468(CHEMBL6151179)
Affinity DataIC50: 3.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657468BDBM50657468(CHEMBL6151179)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK3(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657468BDBM50657468(CHEMBL6151179)
Affinity DataIC50: 167nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed