BDBM50657480 CHEMBL6134606

SMILES COc1cc(OC)c2cc(C(=O)NS(=O)(=O)c3ccccc3-c3ccccc3)oc2c1

InChI Key InChIKey=VDJHRLPVQFOQDN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50657480   

TargetHistone acetyltransferase KAT6A(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657480BDBM50657480(CHEMBL6134606)
Affinity DataIC50: 99nMAssay Description:Inhibition of KAT6A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone acetyltransferase KAT6A(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657480BDBM50657480(CHEMBL6134606)
Affinity DataIC50: 99nMAssay Description:Inhibition of his-tagged human recombinant KAT6A (194 to 810 residues) expressed in baculovirus-infected Sf9 insect cells using H4-derived peptide as...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone acetyltransferase KAT6B(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657480BDBM50657480(CHEMBL6134606)
Affinity DataIC50: 242nMAssay Description:Inhibition of KAT6B (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone acetyltransferase KAT6B(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657480BDBM50657480(CHEMBL6134606)
Affinity DataIC50: 242nMAssay Description:Inhibition of C-terminal human recombinant KAT6B (431 to end residues) expressed in baculovirus-infected Sf9 insect cells using H4-derived peptide as...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone acetyltransferase KAT6A(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657480BDBM50657480(CHEMBL6134606)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KAT6A in human MVLN cells assessed as decrease in estrogen receptor level incubated for 24 hrs by gene reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone acetyltransferase KAT6A(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657480BDBM50657480(CHEMBL6134606)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KAT6A in human MVLN cells assessed as decrease in estrogen receptor level incubated for 24 hrs by gene reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed