BDBM50657727 CHEMBL6152747

SMILES O=C1NCCCCN[C@@H]2CC[C@H](C2)Nc2ncc(C(F)(F)F)c(n2)-c2c[nH]c3cc1ccc23

InChI Key InChIKey=YLHHXTKLLQPHBF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657727   

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657727BDBM50657727(CHEMBL6152747)
Affinity DataKd:  0.140nMAssay Description:Binding affinity to CDK7/CyclinH (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50657727BDBM50657727(CHEMBL6152747)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of CDK7/CyclinH/MAT1 (unknown origin) in presence of ATP by kinase activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed