BDBM50657745 CHEMBL6144337

SMILES CN1CCN(c2sc(S(=O)(=O)C3CCC3)nc2S(=O)(=O)c2ccccc2Cl)CC1=O

InChI Key InChIKey=ABHAJOWSSBIAKI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657745   

TargetNuclear factor erythroid 2-related factor 2(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657745BDBM50657745(CHEMBL6144337)
Affinity DataEC50:  62.2nMAssay Description:Inhibition of Keap1/Nrf2 protein-protein interaction in human HepG2 cells transfected with beta-lactamase under the control of ARE incubated for 16 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657745BDBM50657745(CHEMBL6144337)
Affinity DataEC50:  463nMAssay Description:Inhibition of human Keap1/PL-tagged human Nrf2 protein-protein interaction in human PathHunter U2OS Keap1-NRF2 Nuclear Translocation cells assessed a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed