BDBM50657760 CHEMBL6148660

SMILES CSc1nc(-c2cccc(NC(=O)c3cccc(O)c3)c2)c(-c2ccnc(NC(C)=O)c2)[nH]1

InChI Key InChIKey=ODESFWUAWDIXAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50657760   

TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657760BDBM50657760(CHEMBL6148660)
Affinity DataIC50: 5.20nMAssay Description:Reversible inhibition of EGFR L858R mutant (696 to 1022 residues) (unknown origin) extracted from baculovirus infected Sf9 insect cells in presence o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657760BDBM50657760(CHEMBL6148660)
Affinity DataIC50: 10nMAssay Description:Reversible inhibition of wildtype EGFR (696 to 1022 residues) (unknown origin) extracted from baculovirus infected Sf9 insect cells in presence of AT...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657760BDBM50657760(CHEMBL6148660)
Affinity DataIC50: 51nMAssay Description:Reversible inhibition of EGFR L858R/T790M mutant (696 to 1022 residues) (unknown origin) extracted from baculovirus infected Sf9 insect cells in pres...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657760BDBM50657760(CHEMBL6148660)
Affinity DataIC50: 54nMAssay Description:Reversible inhibition of EGFR L858R/T790M/C797S mutant (696 to 1022 residues) (unknown origin) extracted from baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed