BDBM50657761 CHEMBL6164416

SMILES CCc1nc(-c2cccc(NC(=O)c3cccc(O)c3)c2)c(-c2ccnc(NC(C)=O)c2)[nH]1

InChI Key InChIKey=XUGXQXZREYOOCZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50657761   

TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657761BDBM50657761(CHEMBL6164416)
Affinity DataIC50: 2.90nMAssay Description:Reversible inhibition of EGFR L858R mutant (696 to 1022 residues) (unknown origin) extracted from baculovirus infected Sf9 insect cells in presence o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657761BDBM50657761(CHEMBL6164416)
Affinity DataIC50: 10nMAssay Description:Reversible inhibition of wildtype EGFR (696 to 1022 residues) (unknown origin) extracted from baculovirus infected Sf9 insect cells in presence of AT...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657761BDBM50657761(CHEMBL6164416)
Affinity DataIC50: 210nMAssay Description:Reversible inhibition of EGFR L858R/T790M mutant (696 to 1022 residues) (unknown origin) extracted from baculovirus infected Sf9 insect cells in pres...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed