BDBM50657778 CHEMBL6146710

SMILES C=CC(=O)Nc1ccc(OC)c(Nc2cc(-c3[nH]c(SC)nc3-c3cccc(NC(=O)c4c(F)ccc(O)c4CN4Cc5ccccc5C4=O)c3)ccn2)c1

InChI Key InChIKey=YNMSPOFPLYDBPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50657778   

TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657778BDBM50657778(CHEMBL6146710)
Affinity DataIC50: 1.60nMAssay Description:Irreversible inhibition of EGFR L858R/T790M/C797S mutant (696 to 1022 residues) (unknown origin) extracted from baculovirus infected Sf9 insect cells...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed