BDBM50657844 CHEMBL6148980

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2c(=O)n(C3CC3)c(C)cc21

InChI Key InChIKey=HMVHMNXJAWUUIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657844   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657844BDBM50657844(CHEMBL6148980)
Affinity DataIC50: 4.40nMAssay Description:Binding affinity to recombinant human PKMYT1 incubated for15 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657844BDBM50657844(CHEMBL6148980)
Affinity DataIC50: 622nMAssay Description:Inhibition of CDK1 phosphorylation in human HCC1569 cells incubated for 6 hrs by In-cell Western assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed