BDBM50658075 CHEMBL6149976

SMILES N=C(N)N1CCN(c2cnc(Sc3cccc(Cl)c3Cl)c(N)n2)CC1

InChI Key InChIKey=IRLYVPGHYPHHMW-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50658075   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658075BDBM50658075(CHEMBL6149976)
Affinity DataKd:  740nMAssay Description:Binding affinity to 4PCP WAVE chip-immobilized His-tagged full-length recombinant SHP2 (unknown origin) assessed as equilibrium dissociation rate by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658075BDBM50658075(CHEMBL6149976)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed